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Dr Pan

DRPAN

₹20.00

PACK:  : Strip of 10 tablets.

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Product Description

COMPOSITION :  Each Tablet  contains :-

Pantoprazole  40 mg

M.O.A

Pantoprazole belongs to a class of drugs known as proton pump inhibitors. It acts by reducing the amount of acid produced in the stomach.

PHARMACODYNAMICS:

Pantoprazole is a substituted benzimidazole indicated for the short-term treatment (up to 16 weeks) in the healing and symptomatic relief of erosive esophagitis. Pantoprazole is a proton pump inhibitor (PPI) that suppresses the final step in gastric acid production.

Absorption :

Pantoprazole is well absorbed. It undergoes little first-pass metabolism resulting in an absolute bioavailability of approximately 77%.

Protein binding : 98%

Metabolism

Pantoprazole is extensively metabolized in the liver through the cytochrome P450 (CYP) system. The main metabolic pathway is demethylation, by CYP2C19, with subsequent sulfation; other metabolic pathways include oxidation by CYP3A4. There is no evidence that any of the pantoprazole metabolites have significant pharmacologic activity.

Elimination:

After administration of a single intravenous dose of 14C-labeled pantoprazole to healthy, normal metabolizer subjects, approximately 71% of the dose was excreted in the urine with 18% excreted in the feces through biliary excretion.                                     

 INDICATION  : Gastro- oesophageal reflux disease

DOSAGE  : As directed by the physician

SIDE EFFECTS

Vertigo, Fracture of the hip, Wrist or spine, Pruritis, Pyrexia, Diarrhea, Blurred vision, Dizzines

 

SIMILAR PRODUCTS

Sr No SIMILAR PRODUCTS COMPANY MRP / Tab
1 Pantocid Sun Pharma 79/10
2 Pantosec Cipla 91.50/10
3 Pantop Aristo Pharma 70.67/10
4 Pantodac Zydus(alidac) 79.20/10

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