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DR LIPID FB

DR LIPID FB

₹35.00

PACK : Strip of 10 tablets.

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Product Description

COMPOSITION:  :  Each Tablet  contains:-

ATORVASTATIN   10 mg

FINOFIBRATE  160 mg

M.O.A. : Atorvastatin blocks the action of the enzyme (HMG-CoA reductase) that is required for the production of cholesterol in the body. It thus lowers the level of blood lipids such as cholesterol and triglycerides.

Fenofibrate belongs to a class of drugs called as fibrates or fibric acid derivatives. It works by increasing the action of enzyme lipoprotein lipase which decreases the level of fats (triglycerides) in the blood.

Pharmacodynamics

Atorvastatin competitively inhibits HMG-CoA reductase, the enzyme that catalyses the conversion of HMG-CoA to mevalonic acid. HMG-CoA reductase inhibitors increase HDL-C and decrease LDL-C, VLDL-C and plasma triglycerides. Fenofibric acid, active metabolite of fenofibrate, lowers plasma triglycerides by inhibiting TG synthesis, resulting in the reduction of VLDL-C. Also, it stimulates the catabolism of VLDL-C. It reduces serum uric acid levels by increasing the urinary excretion of uric acid.

Pharmacokinetics

Absorption: Atorvastatin: Rapid absorption after oral admin. Absolute bioavailability: 14%. Fenofibrate: Well absorbed after oral admin.
Distribution: Atorvastatin: >98% bound to plasma proteins. Fenofibrate: About 99% bound to plasma

proteins.
Metabolism: Atorvastatin: Extensively metabolised. Fenofibrate: Rapidly hydrolysed by esterases to the active metabolite, fenofibric acid.
Excretion: Atorvastatin and its metabolites: Removed mainly in the bile. Mean elimination half-life: About 14 hr. Fenofibrate: Mainly removed in the urine as metabolites; fenofibric acid has an elimination half-life of about 16 hr.

INDICATION  : Mixed dyslipidaemia.

DOSAGE:  As directed by the physician

SIDE EFFECTS : Pain in upper central abdomen, Nausea and/or vomiting, Back/ joint or pain in arms and legs, Blistering and peeling of skin, Constipation and diarrhea, Extreme weakness, Abdominal or stomach pain, Abnormally high fever, Muscle pain, Heartburn, And headache

SIMILAR PRODUCTS

Sr No SIMILAR PRODUCTS COMPANY MRP / Tab
1 Storfib Ranbaxy (CARDIOVASCULARS) 173/10
2 Lipikind-F Mankind Pharma 46.2/10
3 Stator-F AHPL 93.3/10
4 Xtor-F Ipca Lab 145.40/10

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